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Our team of experienced radiologists have helped countless patients improve their digestive health through gastrointestinal and urological imaging with the latest technology. With our state-of-the-art clinic, our expert interventional radiologists provide non-surgical alternatives to diagnose and treat a variety of medical needs, from Peripheral Arterial Disease to spider veins. Our team of fellowship trained with CAQ certified additional qualification radiologists are proud to offer interventional radiology as treatment for peripheral artery disease PAD to patients across southeastern NC.

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Our expert radiologists treat your child with compassion and care. With advanced technology and imaging techniques, we can accurately detect and treat problems with the nervous system, spinal cord, spine, head, or neck. At Valley Radiology, we're dedicated to providing a wide range of diagnostic and treatment imaging services for a variety of women's health concerns. When it comes to protecting yourself from breast cancer, early detection is key.

Our women's interventional procedures include: Breast Biopsy Core Needle Biopsy A core needle biopsy is most often minimally traumatic and less expensive than a surgical or open biopsy. As the number of screening Now Available in Clinic! If you have been diagnosed with uterine fibroids, you may be looking for an alternative treatment to a hysterectomy.

Uterine fibroid embolization UFE is a minimally invasive procedure with a It seemed like an urban myth that the type of opioid was what made it dangerous, so that led us to do the study to see if there was evidence for that. Response: Some individuals prescribed opioid analgesic medications for pain develop opioid use disorder. So, much research has been conducted to develop strategies to identify patients who can be safely prescribed opioid analgesics. However, this research has not been critically reviewed through rigorous quality assessment.

Response : "Magic Mouthwash" is one of the most commonly prescribed medications for oral mucositis pain during cancer therapy, but there has not been good evidence in the past to support its use. This trial is the first large randomized controlled trial to demonstrate that both "Magic" mouthwash and doxepin rinse reduce patient reported pain during cancer therapy.

Response: Pediatric tonsillectomy is a commonly performed procedure, representing the second most common ambulatory surgery performed on children in the United States, with over half a million children undergoing the surgery annually. A major concern for surgeons, patients, and their families is the issue of postoperative pain control as pain can last up to days after surgery, be quite severe, and result in readmission to the hospital or ED visits for medications and dehydration. In young children and children with sleep apnea we cannot safely administer narcotic pain medications at home.

This leaves limited options for pain control, including acetaminophen and ibuprofen. However, there are concerns that ibuprofen could potentially increase bleeding risk after surgery because of its effects on platelet function in the blood. At baseline, the risk of postoperative hemorrhage within the first two weeks after tonsillectomy is around 4.

Our study set out to show that the risk of severe postoperative bleeding when ibuprofen is given for 9 days after tonsillectomy was not increased compared with the bleeding risk when acetaminophen was administered instead. Our study could not conclude that the risk of bleeding is no different when ibuprofen is used, and was suggestive that the bleeding risk may actually be higher.

Response: Recent mortality trends in the U. At the same time, multimodal analgesia, the administration of anesthetic agents and medications agents targeting multiple pain pathways, has seen increased popularity in pain management after hip replacement surgery. At Hospital for Special Surgery HSS , the multimodal protocol entails the use of several different anesthetic agents and medications both during and after surgery to control pain, minimize the use of opioids and reduce side effects.

The use of non-opioid analgesics such as acetaminophen allows for a reduction in opioid administration after surgery [1].

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Acetaminophen, commonly known as Tylenol, has traditionally been administered orally, but more recently an intravenous IV preparation has become available. Unless a patient is unable to take acetaminophen, it is commonly used as part of the multimodal protocol due to its efficacy and minimal contraindications.

Although intravenous IV acetaminophen presents pharmacokinetic benefits, such as increasing both serum blood and cerebrospinal fluid levels more rapidly, there is limited analysis of its potential clinical advantages compared to oral acetaminophen. Response: The past research literature has provided relatively little information on the appropriate level of concern regarding non-steroidal anti-inflammatory drugs NSAIDs and kidney disease risk among younger, apparently healthy patients.


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Clinicians are generally most concerned about the effects of these medications on the kidneys among patients with existing renal impairment and persons at risk for it, especially older patients. Given that NSAID use appears to be high and rising in the US, we were interested in developing evidence on this topic in a population of working-age adults. Columbia, SC MedicalResearch.

Response: Even though Migraine with aura was associated with an increased risk of ischemic stroke in the Atherosclerosis Risk in Communities study ARIC , our post-hoc showed unexpected results that onset of such migraines before age 50 years is not associated with such risk. Instead, later onset of migraine with aura after age of 50 was linked with a higher risk of ischemic stroke.

Total of migraineurs with aura MA and migraineurs without aura MO among 11, participants were included in the analysis.


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There was a two-fold increased risk of ischemic stroke when the age of migraineurs with aura onset was 50 years or older as compared with no headache participants, MO was not associated with increased stroke risk regardless of age of onset. Author Interviews , C. Scoville Jr.

Antibiotic use is a major risk factor for CDI but epidemiological studies suggest that other factors, some modifiable, some not, can also increase the risk for CDI. Older age is an example of a non-modifiable risk factor for CDI. Some epidemiological studies suggested that taking the prostaglandin synthesis inhibiting drugs called non-steroidal anti-inflammatory drugs NSAIDs might also increase the risk for CDI. NSAIDs include medications such as ibuprofen, naproxen, indomethacin, and others. Because NSAID use is so common, if it is a risk factor for the acquisition of, or severity of, CDI, that would be important because that would be a modifiable risk factor.

Response: Lumbar spinal stenosis LSS is one of the fastest growing problems in the country due to its aging population. One third of Medicare users have the condition, and it is the number one reason for spine surgery in this population. Existing research evaluates the benefits of nonsurgical treatment options compared to surgery, but there was no existing research that compared the available nonsurgical options to each other to determine the best course of treatment for each patient.

We assessed each of these treatment methods with a questionnaire, a walking distance test, and a physical activity monitor.

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Because migraine has also been associated with factors related with insulin resistance and type 2 diabetes, an association between migraine and diabetes has been hypothesized. We observed a lower risk of type 2 diabetes in women with active migraine. We also show a linear decrease of migraine prevalence long before and a plateau long after type 2 diabetes diagnosis.

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Response: Disc Herniation in the lumbar region can create intense pain in the lower back and along the leg as a result of nerve compression. However, most of the people despite the intense pain would possibly avoid surgery. Incidence of retreatment or cross-over was significantly higher in the injection only group. Response: Musculoskeletal Pain as a result of common problems affecting the back, neck, shoulder, knee and multi-site pain is an increasing cause of reduced function and quality of life, and ever increasing demands on healthcare, Prognosis is often poor with many people reporting persistent symptoms after consulting their primary care practitioner.

The likelihood of persistent and recurrent clinical symptoms may accentuate the physical, psychological, and social impacts of musculoskeletal pain particularly with the middle aged and elderly populations. Pilates is an exercise approach that has become increasingly popular in recent years and includes over fifty different exercises to improve flexibility, balance, core strength, core stability.

It can therefore can be individualised for people with different needs, preferences, musculoskeletal conditions, ages and abilities. Many physiotherapists such as sydney physio solutions have started to specialise in this as a form of treatment, click here for more info on pilates and the many benefits they can have on your physical health. This study investigated the personal experiences and perceptions of the impact of Pilates on the day-to-day lives of adults with a myriad of chronic MSK conditions following a 12 week Pilates Exercise Programme.

The results were organised into five main themes: 1. Physical Improvements strength, core stability, flexibility and balance. Psychosocial benefits and improved confidence, 4. Increased Autonomy in Managing their own Musculoskeletal Condition and 5. Motivation to continue with exercise. Readers should understand that patients Nirmal B. In the United States, over million surgical procedures are performed every year. Adequate treatment of post-operative pain has been shown to improve clinical and economic outcomes, thus there has been an increased effort towards improving post-operative pain control.

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Patients believe that opioid medications will be most effective in treating postoperative pain compared to non-opioid medications, which could be contributing to the opioid epidemic. This difference was not observed in patients expecting prescriptions for non-opioid pain medications.

Parents are less anxious about Response: Migraine is a genetic disorder characterized by recurrent and intense headaches often accompanied by visual disturbances. Genome-wide association studies GWASs are a powerful hypothesis-free tool for investigating the genetic architecture of human disease. Currently, multiple GWASs have been conducted on European adults with migraine that have successfully identified several migraine susceptibility genes involved in neuronal and vascular functions.

Considering the prevalence of migraines varies across ethnicities, the genetic risk factors may be different in patients of African ancestries and European ancestries. In addition, if migraine presents at an early age childhood , it may reflect elevated biological predisposition from genetic factors or increased susceptibility to environmental risk factors.

We performed the first GWAS to investigate the susceptibility genes associated with migraine in African-American children. The main out come was that common variants at the 5q The genetic underpinnings at this locus responsible for this finding are less relevant in patients of European ancestry.

Albrecht, Ph. Can you briefly describe what is meant by fibromyalgia? Response: Fibromyalgia FM is a poorly understood chronic condition characterized by widespread musculoskeletal pain, fatigue, unrefreshing sleep, memory deficits and attention difficulties, among other symptoms. FM affects an estimated 4 million adults in the U. Part of the reason for the paucity of effective therapeutics is insufficient knowledge of the underlying mechanisms contributing to FM.

Previous work from co-senior author of the current manuscript, Eva Kosek, MD, PhD, and collaborators at the Karolinska Institute in Sweden found elevated inflammatory molecules in the cerebrospinal fluid of FM patients, which could be reflective of brain neuroinflammation in these patients.

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However, no study had directly assessed the presence of neuroinflammation in the brain of FM patients. Co-senior author of the study, Marco Loggia, PhD, and collaborators showed in a Brain publication that individuals with chronic low back pain cLBP exhibit evidence of brain neuroinflammation, specifically activation of glial cells. Loggia sought to extend these finding in cLBP to FM, hypothesizing that activation of glial cells may also be associated with FM pathology.

During a conference where I was presenting preliminary results of the fibromyalgia study, Dr. Loggia met with Dr. They decided to form a collaboration, and logistic talks began to determine the best strategy to combine and analyze the separate datasets.